Interpretation of 1D & 2D NMR Spectra

Price

$ 1975
Interpretation of 1D & 2D NMR Spectra

About Course

Although a basic knowledge of chemical shifts and very simple interpretation of 1st-order spectra will be assumed, the general features of proton and carbon spectra will be reviewed with emphasis on the use of chemical shifts and coupling constants for the identification of unknown compounds. This will be followed by the use of proton decoupling procedures, magnetic non-equivalence, relaxation time measurements and NOE.

The second portion of the course will concentrate on the general features and interpretation of 2D homo- and heteronuclear J-delta and chemical shift correlation spectra.

At the end of the course, six final structure problems demonstrate lessons learned throughout the course using both 1D and 2D spectra. 

The course corrects many widely held misconceptions that can lead to improper operation. 

Course content

videoWelcome Buy Now
videoCourse Book and Homework Buy Now
video01-1: Table of Nuclear Spins Buy Now
video01-2: Nuclear Energy Levels Buy Now
video01-3: Macroscopic Magnetization Vector Buy Now
video01-4: NMR Frequency Table Buy Now
video01-5: Generation of NMR Signal Buy Now
video01-6: Coil Shapes Buy Now
video01-7: Shielding Buy Now
video01-8: Chemical Shift Anisotropy Buy Now
video02-1: Typical Proton Chemical Shifts Buy Now
video02-2: Proton Additivity Constants Buy Now
video02-3: Chemical Shifts for Methylene Groups Buy Now
video02-4: Additive Shielding Increments for Olefins Buy Now
video02-5: Substituent Chemical Shifts in Benzenes Buy Now
video02-6: Hydrogen Bonding Buy Now
video02-7: Solvent Effects on Chemical Shifts Buy Now
video02-8: ASTM Standard Practice for Referencing Buy Now
video03-1: Factors Buy Now
video03-2: Typical 13C - Chemical Shifts in Organic Compounds Buy Now
video03-3: Substituent Effects and Additivity Rules: Alkanes Buy Now
video03-4: Substituent Effects and Additivity Rules: Substituted Alkanes Buy Now
video03-5: Substituent Effects and Additivity Rules: Alkenes Buy Now
video03-6: Substituent Effects and Additivity Rules: Benzenes Buy Now
video03-7: Substituent Effects and Additivity Rules: Pyridines Buy Now
video03-8: Substituent Effects and Additivity Rules: Cyclohexanes Buy Now
video03-9: Proton and 13C Chemical Shifts of Some Unsaturated Cyclic Systems Buy Now
videoProblem Solving: Question 1 Buy Now
videoProblem Solving: Answer 1 Buy Now
videoProblem Solving: Question 2 Buy Now
videoProblem Solving: Answer 2 Buy Now
video04-01: Chloroform 1H Line Shape and Hump Test Buy Now
video04-02: Energy Level Diagram for a Coupled Two-Spin System Buy Now
video04-03: Energy Levels in an AX System Buy Now
video04-04: Definition, Signs and Simple Theory of Scalar Coupling Buy Now
video04-05: First-Order Rules and Pascal's Triangle Buy Now
video04-06: Splitting Triangle When I = 1 Buy Now
video04-07: Coupling with Two or More Different Nuclei Buy Now
video04-08: Weak Coupling Buy Now
video04-09: Strong Coupling Buy Now
video04-10: Deviation From First-Order Rules Buy Now
video04-11: 60, 90, and 220 MHZ 1H Spectra of n-butylvinylether in CDCl3 Buy Now
video04-12: Characteristic Proton-Proton Coupling Constants Buy Now
video04-13: Selected Values of Vicinal Coupling Constants in Olefinic & Aromatic Systems Buy Now
video04-14: Selected Values of Vicinal Coupling Constants across Saturated Bonds Buy Now
video04-15: The Effect of Substituents Buy Now
video04-16: Selected Examples of Geminal Coupling Constants Buy Now
video04-17: Selected Examples of Long-range HH Couplings Buy Now
video04-18: Couplings Through Four Saturated Bonds Buy Now
video04-19: Crotonaldehyde Spectrum at 300 MHz Buy Now
video04-20: Heteronuclear Coupling Constants Buy Now
video04-21: 2D Homonuclear J-Resolved Spectra Buy Now
video04-22: Methyl Region of the ID Proton Spectrum Buy Now
video04-23: 2D Homonuclear J-Resolved Spectrum of Coumarin Buy Now
video05-01: One-Bond Proton-Carbon Coupling Constants Buy Now
video05-02: Some Characteristic 1JCH Couplings Buy Now
video05-03: 2D Heteronuclear J-Resolved Spectra Buy Now
video05-04: Attached Proton Test - APT Buy Now
video05-05: DEPT Buy Now
video05-06: Two- and Three-Bond Proton-Carbon Coupling Constants Buy Now
video05-07: Carbon-Carbon Coupling Constants Buy Now
video05-08: Carbon-Heteronuclear Coupling Constants Buy Now
video05-09: Carbon-Phosphorus Coupling Constants Buy Now
video05-10: Structural Features and Carbon-Phosphorus Couplings Buy Now
video05-11: Proton-Coupling Buy Now
video06-01: Effects of Decoupling Power Buy Now
video06-02: Exchanging Nuclei Buy Now
video06-03: 60 MHz 1H Spectrum of Ethanol Buy Now
video06-04: Effect of Proton Decoupling on the 1H Spectrum of Crontonaldehyde Buy Now
video06-05: Decoupled Spectra of an Unsaturated Lactone Buy Now
video06-06: Decoupled Spectra of a Pyranoside Buy Now
videoHomonuclear Correlations Buy Now
video06-07: COSY-90 Spectrum of Glutamic Acid Buy Now
video06-08: 11B COSY Buy Now
video06-09: COSY Spectrum of 9-Hydroxytricyclodecan-2, 5-dione Buy Now
video06-10: COSY for Long Range Coupling Buy Now
video06-11: H-Relayed H,H-COSY Spectrum of Glutamic Acid Buy Now
video06-12: Relayed Coherence Transfer Buy Now
video06-13: Double quantum Filtered COSY Buy Now
video06-14: t1 Noise Buy Now
video06-15: COSY Artifacts Buy Now
video06-16: An Example of lmproper Phase Cycling Buy Now
video06-17: About Homework Buy Now
video06-18: 2D INADEQUATE Buy Now
video06-19: Intentionally Folded INADEQUATE Spectra Buy Now
video06-20: Problem Solving Buy Now
video07-01: Selective Decoupling Buy Now
video07-02: Heteronuclear Chemical Shift Correlation: Coumarin in CDCl3 Buy Now
video07-03: Indirect Detected Heteronuclear Correlation Spectroscopy Buy Now
video07-04: Comparison of HMQC and HSQC spectra Buy Now
video07-05: Accidental Proton Shifts in HETCOR Buy Now
video07-06: Heteronuclear Correlation Via Long Range Coupling Buy Now
video08-01: Scalar vs Dipolar Coupling Buy Now
video08-02: Proton-Decoupled Carbon Spectrum Buy Now
video08-03: Pamoic Acid - Proton Spectrum Buy Now
video08-04: Pamoic Acid - NOE Difference Spectrum Buy Now
video09-01: AA 'XX' Spectrum Buy Now
video09-02: Analysis of an AA 'XX' System Buy Now
video09-03: Magnetic Equivalence Problems Buy Now
video09-04: Magnetic Equivalence Answers Buy Now
video09-05: Acetylene - 1,2 - 13C2 Proton Spectrum Buy Now
video09-06: Non-Equivalent AB Protons Buy Now
video09-07: Spectrum of Trimethylcitrate Buy Now
video09-08: Virtual Coupling Buy Now
video09-09: Example of Structure Determination Using NOE Difference Buy Now
video09-10: Example of Structure Determination Using NOE Difference (Cont'd) Buy Now
video10-01: Calculated AB Spectra Buy Now
video10-02: The 60 MHz 1H Spectrum of Abel's Ketone in CDCl3 Buy Now
video10-03: Crotonaldehyd Spectrum at 60 MHz Buy Now
video10-04: Calculated AB2 Spectra Buy Now
video10-05: The 60 MHz 1H Spectrum of 2,6-Dichlorophenol Buy Now
video10-06: Analysis of an ABX Spectrum Buy Now
video10-07: The 60 MHz 1H Spectrum of Malic Acid & the CH2CH Proton of a Substituted Cycloproprane Buy Now
video10-08: The Spectrum of Malic Acid at Different Field Strengths Buy Now
video10-09: Strong Coupling in 2D INADEQUATE Spectra Buy Now
video10-10: Strong Coupling Effects in 2D J,(delta) Spectra Buy Now
video10-11: Example Problem Buy Now
video11: Spectrum of an Optically Active Isomer; Effect of Chiral Shift Reagent on Pure R-Isomer; Spectrum of a Racemic Mixture; Effect of Chiral Shift Reagent on Racemic Mixture Buy Now
video12-01: Basic Relaxation Concepts Buy Now
video12-02: Longeitudinal Relaxation Time, T1 Buy Now
video12-03: Measurement of T1 Buy Now
video12-04: T1 Spectra Buy Now
video12-05: Relaxation Mechanisms Buy Now
video12-06: Dipole-Dipole and Spin Rotation Contributions Buy Now
video12-07: Contributions to Dipole-Dipole Relaxations: Number of Protons Buy Now
video12-08: Assignment Answers Buy Now
video12-09: Contributions to Dipole-Dipole Relaxations: Correlation Time Buy Now
video12-10: Contributions to Dipole-Dipole Relaxations: Dipole-Dipole Relaxation Time vs Correlation Time Buy Now
video12-11: Contributions to Dipole-Dipole Relaxations: Inversion Recovery 13C Spectrum of Cholestane Buy Now
video12-12: Electric Quadrupole Relaxation Buy Now
video12-13: Effect of Correlation Time on O-17 Spectra Buy Now
video12-14: Effect of Anisotropic Overall Motion Buy Now
video12-15: Some Characteristic 13C T1 Values Buy Now
video12-16: T1 Data for Aniline in different Solvents Buy Now
video12-17: Effect of Cr (III) and Cu (II) Buy Now
video13-01: Effect of NOE on Integration Buy Now
video13-02: Nuclear Overhauser Enhancement Buy Now
video13-03: Measuring the NOE Buy Now
video13-04: Coupled spectra With NOE Buy Now
video13-05: Pulse Sequence in Gated Decoupling Experiments Buy Now
video13-06: Incomplete NOEs Buy Now
video13-07: Measuring T1DD Buy Now
video13-08: Assignment of Quaternary Carbons in Benzonitrile Buy Now
video13-09: Integration of Carbon Spectra Buy Now
video14-01: Dependence of Maximum Homonuclear NOE on Correlation Time Buy Now
video14-02: Reduction of the Steady-State NOE with Distance Buy Now
video14-03: NOE in Three-Spin Systems Buy Now
video14-04: Dependence of NOE on Correlation Time and Mixing Time Buy Now
video14-05: NOESY and ROESY Peaks vs Correlation Time Buy Now
videoProblem 1: Sulcatol Buy Now
videoAnswer 1 Buy Now
videoProblem 2: C8H9NO2 Buy Now
videoProblem 3: Structure Elucidation of an Unknown Hydrocarbon Buy Now
videoProblem 4: Pamoic Acid - Make all carbon line assignments Buy Now
videoProblem 5: Tripeptide - Make proton and carbon line assignments Buy Now
videoProblem 6: C18H20O6 - Make proton and carbon line assignments Buy Now
videoCourse Homework Answers Buy Now
videoFarewell Buy Now
Daniel D Traficante

Daniel D Traficante

Emeritus Professor of NMR

Course Instructor

Dr. Traficante obtained his Ph.D. in 1962 from MIT in the field of synthetic organic chemistry. For 10 years he was Director of the NMR Lab at MIT, and then held the same position at Yale University. Serving as the Director of Chemical Instrumentation at the National Science Foundation (NSF),he pioneered multi-nuclear instrumentation. He has built probes, reassembled spectrometers, and developed new software programs to enhance the signal-to-noise ratio and the resolution of NMR spectra. He received a Letter of Commendation from the Chemistry Division when he left the NSF to return to teaching. 
 

At NMR Concepts, his current research in the areas of structure determination, instrumentation and data processing provide him with knowledge and expertise that are applicable to a broad audience. His organic chemistry background, plus his expertise in electronics, gives his lectures a special depth and appreciation for the field. Dr. Traficante is known throughout the world as an outstanding educator.

Mastering NMR Concepts

This bundle includes։

Courses։ 2

Price

$ 2675 $ 2972